Glands & Lymphoid tissue
Anatomy · Topic 70
Source: NMC CBME Curriculum 2024 · Volume I · Anatomy · Topic 70 · combined PDF page 145
Practice questions
- A patient with longstanding Sjögren syndrome develops persistent bilateral parotid enlargement. Which MALT lymphoma association is most directly supported by the supplied review?
- A patient with chronic autoimmune thyroiditis is being evaluated for a thyroid extranodal marginal-zone lymphoma. Which associated condition is highlighted in the review?
- Which statement best characterizes the reported relationship between Chlamydia psittaci and ocular-adnexal MALT lymphoma?
- A patient with chronic airway inflammation is found to have pulmonary MALT lymphoma. Which organism is identified in the review as a possible associated pathogen?
- Which organism–site pairing is reported for small-intestinal MALT lymphoma?
- A chronic skin lesion is biopsied and found to represent cutaneous MALT lymphoma. Which infectious association is described in the review?
- Which principle best summarizes the pathogenesis theme shared across the non-gastric MALT lymphoma sites reviewed?
- A biopsy is being assessed for possible MALT lymphoma. Which immunophenotypic pattern most closely matches the pattern reported in the supplied review?
- A lymphoid lesion shows CD20 and CD79a expression, light-chain restriction, and absence of CD5, CD10, and cyclin D1. What is the best interpretation based on the supplied MALT lymphoma review?
- According to the supplied review, what is required for diagnostic evaluation of suspected non-gastric MALT lymphoma?
- In the staging approach summarized by the supplied review, which MALT lymphoma sites are specifically described as using TNM-based staging?
- A clinician is assessing the extent of a non-gastric MALT lymphoma. Which imaging modalities are identified in the supplied review as being used to determine staging and spread?
- A patient has localized non-gastric MALT lymphoma. Which treatment summary most accurately reflects the supplied review without implying a universal protocol?
- Which treatment sequence is specifically described in the supplied review for intestinal MALT lymphoma?
- Which statement best reflects the prognosis and follow-up summary for non-gastric MALT lymphoma in the supplied review?
- Which phenotype is used in the supplied review to characterize age-associated B cells (ABCs)?
- Which combination of signals is reported as required for age-associated B-cell differentiation?
- Which transcriptional regulator is described as a nonredundant master regulator of age-associated B-cell identity?
- A review describes ABCs in inflamed salivary glands as capable of contributing locally to pathology. Which mechanism is included in the supplied review?
- Which set contains only tissue-level contributions attributed to ABCs in the supplied review?
- Which finding is reported in the supplied review concerning age-associated B cells in multiple sclerosis?
- How does the supplied ABC review characterize the possible relationship between Epstein–Barr virus and autoimmunity?
- According to the history summarized in the supplied review, where were age-associated B cells first described?
- A cohort study reports that 80.07% of gastric MALT lymphoma tumors were localized at diagnosis. Which interpretation is most appropriate?
- In the 2010–2021 SEER-based gastric MALT lymphoma study, which age range included most diagnoses?
- Which factors were identified as independent predictors of mortality in the supplied SEER-based gastric MALT lymphoma analysis?
- The gastric MALT cohort found no significant interaction between age and gender on mortality. What does this result mean?
- In the supplied SEER-based gastric MALT lymphoma analysis, radiotherapy was associated with reduced overall mortality. Which conclusion is justified by this finding alone?
- A patient with salivary-gland MALT lymphoma asks whether a case report of parotid regression after dietary and nutraceutical intervention establishes that this is standard treatment. What is the best evidence-based response from the supplied material?
- A researcher finds T-bet+ CD11c+ B cells in inflamed salivary tissue from a patient with autoimmune disease. Which interpretation best fits the supplied ABC review?
- A clinician proposes using a chronic inflammatory association alone to diagnose MALT lymphoma in an enlarged salivary gland. Which response best aligns with the supplied evidence?
- Which statement best distinguishes age-associated B cells from the MALT lymphoma immunophenotype described in the supplied review?