Chemistry and Metabolism of Carbohydrates
Biochemistry · Topic 3
Source: NMC CBME Curriculum 2024 · Volume I · Biochemistry · Topic 3 · combined PDF page 162
Practice questions
- Which statement best captures the role of nucleotide sugars in carbohydrate biosynthesis described in the cited review?
- Which pair consists of nucleotide-sugar examples specifically highlighted in the review of Leloir's legacy?
- What was the central discovery for which Luis F. Leloir received the Nobel Prize in Chemistry, as summarized by the cited review?
- According to the cited review, nucleotide sugars serve as sugar donors for which class of enzymes?
- Which pair of plant carbohydrate biosynthetic pathways is specifically described as having been elucidated by Leloir's group?
- In the cited plant review, trehalose 6-phosphate is described as which of the following?
- Which set of carbohydrates was included among the diverse fructan substrates tested with rumen-derived bacteria?
- Which tested rumen-derived bacterium was reported to metabolize levan, with delayed growth?
- Which substrate-use result was shared by all three bacterial species tested in the rumen fructan study?
- In naïve rumen microbial communities exposed to inulin, what pattern in relative abundance was reported for Bifidobacterium and Lactobacillus?
- What did fluorescently labelled polysaccharides (FLAPS) contribute to the fructan study?
- Which conclusion is appropriately limited to the evidence from the cited inulin study?
- The cereal crop fructans discussed in the study were described as which structural type?
- What was the principal advantage of dDNP NMR emphasized in the yeast study?
- On what approximate timescale did the cited in-cell dDNP NMR approach observe carbohydrate influx into central metabolism?
- Which metabolic observation was reported for Hanseniaspora uvarum in the yeast comparison?
- Which yeast was reported to outcompete other biotechnologically relevant yeasts through rapid ethanol formation associated with efficient cofactor-pool adaptation?
- Compared with the rapid ethanol-forming strategy described for S. cerevisiae, what broad metabolic strategy was reported for some other yeasts?
- What did the study conclude about glycolytic logic across the eight biotechnologically important yeasts examined?
- Why did the yeast study emphasize functional assays in addition to genome information?
- Which combination correctly identifies the analytical approach described for targeted phosphorylated-carbohydrate measurement?
- Which set contains only analytes specifically included in the HILIC-QqQ-MS/MS target panel described in the methods chapter?
- Which additional analyte pair, beyond the four sugar phosphates G1P, F6P, M6P, and G6P, was included in the described target panel?
- Why are phosphorylated carbohydrates analytically challenging to measure, according to the methods chapter?
- Which statement about the scope of the HILIC-QqQ-MS/MS chapter is best supported?
- A laboratory wants to distinguish G1P, F6P, M6P, and G6P rather than report them as one undifferentiated pool. Which concern from the methods chapter most directly motivates targeted chromatographic analysis?
- Which cross-study statement is most defensible from the supplied literature?