Pyoderma
Dermatology, Venereology & Leprosy · Topic 15
Source: NMC CBME Curriculum 2024 · Volume II · Dermatology, Venereology & Leprosy · Topic 15 · combined PDF page 361
Practice questions
- A patient has a painful ulcerative skin lesion that is being evaluated as possible pyoderma gangrenosum. Which description best characterizes PG?
- A patient develops rapidly worsening ulcerative wounds after surgery. Cultures are negative, antibiotics have not helped, and the lesions are being treated as a surgical-site infection. Which diagnosis should be actively considered?
- In a review of postsurgical pyoderma gangrenosum following breast surgery, which symptom was most frequently reported?
- A patient develops ulceration after breast surgery. Which finding is a reported clinical clue favoring postsurgical pyoderma gangrenosum?
- A postoperative ulcer has a negative microbiological culture. Which interpretation is most appropriate when considering postsurgical pyoderma gangrenosum?
- A patient with a worsening wound after breast surgery has a markedly elevated C-reactive protein level. Which statement best reflects the supplied evidence on this finding in postsurgical PG?
- In a systematic review of PG after reduction mammoplasty, what was the median time from surgery to initial presentation?
- In a review of postsurgical PG involving combined breast-abdominal procedures, which distribution pattern was reported?
- A patient with suspected postsurgical PG is being considered for wound debridement because the ulcer is enlarging. Which management concern is supported by the supplied reviews?
- A patient has an unexplained, rapidly worsening ulcerative wound after foot and ankle surgery. Which approach is most consistent with the supplied systematic review?
- Which systemic treatment was described as the most common and effective treatment in the supplied review of postsurgical breast PG?
- In a systematic review of PG after reduction mammoplasty, what was the most frequently reported wound-healing approach?
- In the updated systematic review of postsurgical PG following breast surgery, what proportion of cases required surgical reconstruction?
- A systematic review of postsurgical PG after foot and ankle surgery included 10 cases. Which finding was reported in this small case series?
- In the foot-and-ankle postsurgical PG review, what timing was reported for the cases that proceeded to amputation?
- A review of PG after reduction mammoplasty reported associations with which patient characteristics?
- A systematic review and single-arm meta-analysis pooled complete healing outcomes across studies of several systemic PG therapies. What pooled proportion of complete healing did it report?
- In the supplied single-arm meta-analysis of systemic PG therapies, what pooled proportion of recurrence was reported?
- Which pooled proportion of treatment failure was reported across systemic PG treatment studies in the supplied meta-analysis?
- The supplied meta-analysis of systemic PG therapies reported a pooled proportion of serious adverse effects. What was that proportion?
- The pooled complete-healing analysis in a PG treatment meta-analysis had an I² of 66%. Which interpretation best fits this result?
- A clinician compares pooled healing proportions from a single-arm meta-analysis of different systemic PG therapies. Which conclusion is justified by the supplied evidence?
- A report of refractory PG during concurrent dual-targeted therapy describes improvement in the skin lesions. Which conclusion is most appropriate based on the supplied systematic review?
- An international review of published dual-targeted therapy exposures in PG found 14 exposures with extractable PG-specific cutaneous outcomes. All 14 were reported as improved or resolved. What is the most defensible interpretation?
- What did the international multidisciplinary consensus establish for a PG treatment-effectiveness registry?
- Why was a minimum dataset developed for an international PG treatment-effectiveness registry?
- In a systematic review of PG after reduction mammoplasty, the median time to initial presentation was 6.5 days and the median time to diagnosis was 15.5 days. What does this difference most directly illustrate?
- A patient with suspected PG after surgery is being considered for escalating wound-directed procedures. Which principle is best supported by the supplied postsurgical reviews?
- A clinician is discussing systemic treatment evidence for PG with a patient. Which summary most accurately reflects the supplied evidence?
- In the supplied review of concurrent dual-targeted therapy exposures for PG, most reported exposures were associated with which underlying disease context?
- A patient develops bilateral wound dehiscence after reduction mammoplasty. The wounds are unusually painful and continue to worsen despite treatment for infection. Which statement best reflects the relevance of PG in this setting?