Urticaria Angioedema
Dermatology, Venereology & Leprosy · Topic 14
Source: NMC CBME Curriculum 2024 · Volume II · Dermatology, Venereology & Leprosy · Topic 14 · combined PDF page 361
Practice questions
- A patient develops intensely pruritic, raised, blanching plaques that disappear within hours without leaving marks. Which lesion type best describes these lesions?
- A patient has episodic swelling of the lips and tongue without superficial wheals. Which description best distinguishes this finding from a wheal?
- A patient reports recurrent wheals on most days for eight weeks. Using the standard duration-based classification, how should this urticaria be categorized?
- Wheals occur unpredictably without a reproducible external stimulus. Which classification best fits this pattern?
- A linear wheal appears after the skin is stroked with a blunt object. Which diagnosis is most likely?
- A clinician suspects symptomatic dermographism. Which bedside procedure most directly tests the suspected trigger-response relationship?
- Which statement best reflects the evidence on office provocation testing for common physical urticarias?
- A patient develops a delayed painful swelling at sites exposed to sustained pressure. Which inducible urticaria subtype is most consistent with this history?
- Which procedure is specifically reported to have low sensitivity for confirming cholinergic urticaria?
- An adult develops acute urticaria and angioedema after taking an NSAID and reports similar reactions to chemically unrelated NSAIDs. Which phenotype is most consistent with this history?
- Which mechanism is considered important in NSAID-associated urticaria and angioedema, although the full pathogenesis remains incompletely understood?
- A patient with recurrent chronic wheals asks whether a definite cause will usually be found. Which response best reflects evidence on chronic urticaria?
- A patient with chronic spontaneous urticaria has no history suggesting a food or drug trigger and has a normal examination apart from wheals. Which diagnostic approach is most appropriate?
- In a child with chronic urticaria, which circumstance most supports ordering allergy tests?
- A child develops acute urticaria and angioedema soon after a new food exposure, and the history suggests an external trigger. What is the most appropriate next step?
- For a patient with chronic urticaria, which overall treatment strategy best aligns with evidence-based management principles?
- A patient’s chronic urticaria remains poorly controlled and substantially affects daily life despite initial treatment. Which response is most appropriate?
- A patient has recurrent angioedema without wheals. Which diagnostic principle is most important before planning further evaluation?
- A patient with recurrent angioedema is suspected of having a hereditary or acquired angioedema disorder. Which investigation strategy is most appropriate?
- A patient with recurrent angioedema is being evaluated for a possible hereditary disorder. Which approach is least appropriate?
- A patient with a suspected allergic reaction develops acute skin symptoms and respiratory compromise. Which feature makes anaphylaxis more likely than isolated urticaria?
- A patient presents with suspected anaphylaxis. What is the recommended initial treatment?
- After an episode of anaphylaxis, the suspected trigger is identified. Which discharge plan best reflects recommended follow-up principles?
- A patient with chronic spontaneous urticaria has no clear external trigger. Which statement about the likelihood of an external cause is most accurate?
- A clinician wants to follow changes in a patient’s chronic urticaria control and quality-of-life impact over several visits. Which approach is most appropriate?
- What is a key advantage of validated patient-reported outcome measures in chronic urticaria?
- A patient with suspected inducible urticaria has a negative office provocation test despite a convincing history. What is the best interpretation?
- Which pairing correctly matches an inducible urticaria subtype with its relevant provoking procedure or stimulus?
- A study reports suggestive genetic associations with NSAID-induced acute urticaria/angioedema, but no variant reaches genome-wide significance. Which conclusion is most justified?
- A patient with chronic urticaria reports substantial sleep and daily-life impairment despite relatively few visible lesions at today’s visit. Which assessment principle is most appropriate?