Liver disease
General Medicine · Topic 5
Source: NMC CBME Curriculum 2024 · Volume II · General Medicine · Topic 5 · combined PDF page 290
Practice questions
- A woman with cardiometabolic risk factors has steatotic liver disease and reports an average alcohol intake of 200 g/week for the past 4 months. Under the supplied AGA classification framework, which category best fits this alcohol range?
- A man with cardiometabolic risk factors and steatotic liver disease reports alcohol consumption of 300 g/week over the preceding 5 months. Which interpretation is most appropriate under the supplied AGA review?
- A patient with steatotic liver disease had alcohol use assessed at diagnosis, but not during subsequent annual visits. Which approach best aligns with the supplied AGA advice?
- Which combination of methods is supported by the supplied AGA review for assessing alcohol use in a patient with steatotic liver disease?
- A patient with chronic liver disease asks whether continued alcohol intake can affect fibrosis even if the underlying disease is not primarily alcohol-associated. Which response best reflects the supplied AGA review?
- A patient with MASLD has an elevated FIB-4 result. Which next step is most consistent with the supplied 2026 MASLD guideline?
- Which sequence best represents the tiered noninvasive fibrosis strategy described for MetALD in the supplied AGA review?
- A patient with recent ongoing alcohol use has a high liver stiffness measurement on transient elastography. What caveat is emphasized in the supplied AGA review?
- A clinician is evaluating a patient for MASLD and asks whether liver biopsy is required routinely to establish the diagnosis. Which statement best reflects the supplied guideline?
- A patient has discordant noninvasive tests for suspected MASLD-related liver injury, and the result would affect clinical classification. Which role for biopsy is supported by the supplied guideline?
- Which clinical question is a supplied MASLD guideline-supported reason to consider liver biopsy?
- In a MASLD cohort, an ELF result is below 9.00. According to the supplied meta-analysis, which interpretation is most defensible?
- A MASLD patient has an ELF result of 10.0. Which statement best matches the supplied meta-analysis?
- Which ELF threshold was identified in the supplied meta-analysis as a balanced cutoff for identifying cirrhosis (F4) in MASLD?
- Which statement about ELF 7.70 is supported by the supplied MASLD meta-analysis?
- Which strategy is described as the foundation of MASLD management in the supplied 2026 guideline?
- A patient with MetALD is receiving counseling about medical management. Which plan best reflects the supplied AGA advice?
- A patient with MetALD has documented folate, thiamine, and vitamin D deficiencies. Which approach is specifically included in the supplied AGA management advice?
- A patient with MetALD and moderate alcohol use disorder asks about treatment. Which combination is recommended in the supplied AGA review?
- A patient with MetALD asks whether semaglutide has established safety and efficacy for MetALD because it is approved for noncirrhotic MASLD. Which response is most accurate based on the supplied AGA review?
- A patient with MetALD is considering bariatric surgery but expects to continue drinking alcohol after the procedure. Which position is supported by the supplied AGA review?
- A patient with steatotic liver disease reports reducing alcohol intake but has not stopped completely. Which counseling statement is closest to the supplied AGA advice?
- A patient with unexplained liver disease has had other possible causes evaluated without an identified etiology. What is the next diagnostic consideration supported by the supplied autoimmune liver guideline?
- Which statement best describes the role of laboratory testing in the supplied autoimmune liver disease guideline?
- A systematic review of observational studies reports that higher healthy plant-based diet adherence is associated with lower incident MASLD risk. Which conclusion is justified?
- In the supplied meta-analysis of observational studies, which dietary pattern was associated with greater odds or risk of MASLD?
- A clinician is reviewing observational evidence on plant-based diets and liver cancer. Which pattern was reported in the supplied meta-analysis?
- A child with chronic liver disease is being assessed for nutritional compromise. Which pair of assessment approaches is highlighted in the supplied pediatric consensus review?
- Which nutritional concern is emphasized for children with chronic liver disease in the supplied consensus review?
- A patient with MASLD asks whether alpha-lipoic acid should be considered an established disease-modifying therapy. Which conclusion best reflects the supplied systematic review?