Thyroid Dysfunction
General Medicine · Topic 12
Source: NMC CBME Curriculum 2024 · Volume II · General Medicine · Topic 12 · combined PDF page 301
Practice questions
- A clinician is deciding whether to measure TSH in a patient with persistent, nonspecific complaints and in an asymptomatic population without specific risk features. Which statement best reflects the AACE position described in the supplied evidence?
- A health policy committee cites the USPSTF position discussed in the supplied AACE statement. Which rationale for not endorsing routine screening is described there?
- A clinician notes that published recommendations for thyroid testing and treatment in pregnancy use differing reference cut-offs. What was the stated purpose of the SEEN-SEGO consensus document?
- Which set of topics is explicitly included in the SEEN-SEGO consensus document on thyroid dysfunction during pregnancy?
- A patient with pre-existing nodular thyroid disease develops biochemical hyperthyroidism after iodinated contrast exposure. Which interpretation is best supported by the supplied position paper?
- An older adult from a region with a history of iodine deficiency has nodular thyroid disease and is being considered for iodinated contrast imaging. Which feature most supports heightened attention to possible contrast-induced hyperthyroidism?
- A patient develops a mild thyroid-function abnormality after iodinated contrast exposure but has no appreciable symptoms. Which course best matches the most common pattern described in the supplied position paper?
- When considering prevention or treatment of possible iodinated contrast–induced thyroid dysfunction, which approach is recommended in the supplied position paper?
- In a meta-analysis of patients with COVID-19, which thyroid-hormone pattern was associated with more severe disease?
- A hospitalized patient with COVID-19 has a low TSH. Based on the supplied meta-analysis, which conclusion is most appropriate?
- After reviewing evidence that lower FT3 is associated with severe COVID-19, a team proposes routine thyroid-function monitoring as a proven intervention to improve outcomes. Which response best reflects the supplied review?
- In adults with liver failure, which finding was associated with higher mortality in the supplied systematic review and meta-analysis?
- A clinician sees a meta-analysis reporting increased mortality among liver-failure patients with thyroid dysfunction. Which interpretation is most defensible?
- In a meta-analysis of lung-cancer patients receiving immune checkpoint inhibitors, development of treatment-related thyroid dysfunction was associated with which outcome pattern?
- A lung-cancer patient receiving an immune checkpoint inhibitor develops thyroid dysfunction. Which interpretation of the reported survival association is most appropriate?
- Which thyroid dysfunction subtype was the most prevalent among pregnant women in the supplied 2003–2024 systematic review and meta-analysis?
- The supplied meta-analysis estimated pooled thyroid dysfunction prevalence in pregnant women at 16.12%, with I² of 98.16%. What is the most appropriate interpretation of this combination?
- Which statement best matches the pooled subtype estimates for thyroid dysfunction in pregnancy reported by the supplied meta-analysis?
- Which association was reported for clinical hypothyroidism in patients with systemic lupus erythematosus in the supplied systematic review?
- In the supplied SLE review, which pattern was associated with euthyroid sick syndrome?