Tuberculosis
General Medicine · Topic 27
Source: NMC CBME Curriculum 2024 · Volume II · General Medicine · Topic 27 · combined PDF page 321
Practice questions
- In a population TB screening programme, which approach is described as a core screening and triage tool that can improve case detection and referral for confirmatory testing?
- A district clinic wants a decentralised method to detect TB using a molecular platform. Which option is supported by the recent diagnostic review?
- A child with suspected TB cannot produce sputum. Which diagnostic strategy is supported for sputum-scarce populations?
- A patient with advanced HIV and suspected TB is unable to provide a respiratory specimen. Which assay type may improve diagnostic yield in this setting?
- Which test is specifically cited as a rapid molecular approach to drug-resistance testing in the recent TB diagnostics review?
- A reference laboratory needs a comprehensive drug-susceptibility approach for an isolate. Which method is recognised in the supplied review for this purpose?
- A proposed blood biomarker is claimed to distinguish TB infection from TB disease at the point of care. Which statement best reflects the supplied diagnostic review?
- A patient has suspected tracheobronchial TB. Which approach is described as indispensable for confirmed diagnosis?
- During bronchoscopy for suspected tracheobronchial TB, which set of specimens can be obtained for etiological testing according to the guideline?
- A clinician suspects tracheobronchial TB and requests serological immunological tests. How should these results be interpreted under the supplied guideline?
- In a patient with suspected tracheobronchial TB, which imaging review is specifically emphasised in the supplied guideline?
- A patient has ileocaecal ulcero-stricturing disease, and Crohn disease and gastrointestinal TB are both being considered. Which statement best explains why biopsy interpretation can be challenging?
- For adults and adolescents aged 14 years or older with MDR/RR-TB, which six-month regimen is recommended over nine-month or longer regimens in the supplied 2026 guideline?
- A pregnant patient with MDR/RR-TB is being considered for a six-month regimen. Which regimen is specifically recommended by the supplied guideline for MDR/RR-TB patients including pregnant and breastfeeding women?
- An MDR/RR-TB patient has fluoroquinolone-susceptible disease and is eligible for the recommended nine-month all-oral regimen. Which combination matches the regimen specified in the supplied guideline?
- A patient with MDR/RR-TB is not eligible for a recommended short-course regimen. Which approach to selecting a longer regimen is supported by the supplied guideline?
- When starting a long-course regimen for MDR-TB, which composition principle is recommended in the supplied guideline?
- A patient receiving MDR/RR-TB treatment is being monitored for treatment response and toxicity. Which assessment plan best reflects the supplied guideline?
- A patient on a standardized short-course MDR/RR-TB regimen develops a drug adverse reaction. Which response is most consistent with the supplied guideline?
- A person with HIV is receiving treatment for MDR/RR-TB. Which approach to antiretroviral therapy is recommended in the supplied guideline?
- A patient has CNS TB and HIV. According to the supplied MDR/RR-TB guideline, when should ART be initiated after starting anti-TB treatment?
- A healthy adult asks whether BCG revaccination has established benefit against TB infection based on QuantiFERON conversion outcomes. What did the supplied meta-analysis find?
- In the 2024 global estimates cited in a recent TB treatment review, approximately how many people developed TB?
- A public health team is prioritising interventions to reduce TB deaths occurring before treatment begins. Which care gap is highlighted in the supplied review?
- A patient with active tracheobronchial TB has clinically significant airway stenosis. Which treatment principle is recommended?
- Which group of symptoms is described as typical of tracheobronchial TB in the supplied guideline?
- A bronchoscopic biopsy from a suspected TBTB lesion shows compatible histopathology, but acid-fast staining is negative. Which next step is consistent with the supplied guideline?
- A patient with suspected TB is being assessed for screening and definitive diagnosis. Which pairing correctly distinguishes the roles of digital chest radiography and molecular NAATs?