Gastrointestinal and Hepatobiliary system
Microbiology · Topic 4
Source: NMC CBME Curriculum 2024 · Volume I · Microbiology · Topic 4 · combined PDF page 209
Practice questions
- In a meta-analysis of prophylactic negative-pressure wound therapy (NPWT) after gastrointestinal and hepatobiliary-pancreatic abdominal surgery, which pooled finding was reported for overall surgical-site infection compared with standard dressings?
- Which outcome pattern best matches the systematic review of prophylactic NPWT after gastrointestinal and hepatobiliary-pancreatic laparotomy?
- A clinician interprets the reported OR of 0.63 for overall SSI with NPWT as meaning that NPWT lowers absolute SSI risk by 37 percentage points. Which interpretation is most accurate?
- The review of prophylactic NPWT included which combination of study designs and total number of patients?
- Which set contains the extracellular-vesicle-associated non-coding RNA classes considered in the review of gastrointestinal and hepatobiliary cancers?
- A research team proposes that EV-associated non-coding RNAs can influence more than tumor-cell proliferation alone. Which function is explicitly included in the review's tumor-microenvironment framework?
- Which statement best reflects the review's caution about translating EV-associated non-coding RNA findings into clinical practice?
- Why does the EV review caution against generalizing its cholangiocarcinoma discussion to all biliary tract cancers?
- In the orlistat FAERS study, which set of criteria defined a positive disproportionality signal?
- A clinician sees a high ROR for an adverse-event term in the orlistat FAERS analysis. Which conclusion is justified by that finding alone?
- Which adverse-event terms were the two strongest reporting signals in the orlistat FAERS study?
- Which statement accurately describes the population used for disproportionality analyses in the orlistat study?
- How does the supplied review characterize nicotine in tobacco-associated gastrointestinal carcinogenesis?
- According to the nicotine review, which receptor class is activated by nicotine in the proposed gastrointestinal tumor-promoting mechanisms?
- Which group contains pathways described as recurring in nicotine-associated signaling across gastrointestinal tissues in the review?
- A learner attributes tobacco-related mutagenesis in oral and pancreatic tissues directly to nicotine based on the supplied review. Which correction best reflects the review?