CerebralPalsy
Orthopedics · Topic 9
Source: NMC CBME Curriculum 2024 · Volume III · Orthopedics · Topic 9 · combined PDF page 448
Practice questions
- In the randomized trial of intensive upper-limb therapies, which age range did the enrolled children fall into?
- Which functional characteristic was specified for the children enrolled in this trial?
- The children in the trial were described as having which form of cerebral palsy?
- How many children were recruited in total, and how were they allocated between the two groups?
- Which description best identifies the study design used to compare the two therapy sequences?
- From which sources were participants recruited?
- What was the total prescribed dose of intensive upper-limb therapy in each group?
- Which therapy sequence was assigned to the experimental group?
- Which therapy sequence was assigned to the control group?
- Which schedule corresponds to delivery of the 100-hour protocol over the 10-week intervention period?
- Which instrument was used to measure the trial’s primary outcome?
- Which instrument measured the secondary outcome of quality of life?
- A study report identifies bimanual functional performance as its primary endpoint. Which measure in this trial corresponds to that endpoint?
- At which weeks were the four outcome assessments performed?
- At week 8, what increase in AHA units was reported for the experimental group after application of mCIMT?
- After the control group completed bimanual intensive therapy, what increase in AHA units was reported at the corresponding week-8 assessment?
- At week 10, after receiving its mCIMT portion, what was the control group’s greatest reported increase in bimanual functional performance?
- Which interpretation best describes the reported time course of bimanual functional-performance gains across the two groups?
- What was the experimental group’s reported quality-of-life improvement after 80 hours of mCIMT?
- What quality-of-life improvement was reported for the control group after its 20 hours of mCIMT?
- Which outcome had a reported protocol interaction p value of .018?
- The protocol interaction for quality of life was reported as p = .09. Which interpretation is most appropriate using a conventional .05 significance threshold?
- The investigators compared two orders of mCIMT and bimanual intensive therapy while keeping total therapy hours the same. What feature of the comparison does this design most directly address?
- Which statement correctly distinguishes the trial’s primary and secondary outcomes?
- A 6-year-old child with congenital hemiplegia and low bimanual functional performance resembles the trial population. Which conclusion is most defensible when discussing the study’s findings?
- Which feature most limits broad generalization of this trial’s results to children with cerebral palsy?
- The study’s stated question concerned whether the order and dose of mCIMT within a combined protocol influenced outcomes. Which pair of outcomes was assessed?
- The experimental group showed its reported 22-unit AHA increase at week 8, while the control group’s greatest increase was 10.6 units at week 10. Which conclusion best respects this timing difference?
- Which statement about quality-of-life results is consistent with the reported data?
- A reader sees the article’s conclusion that mCIMT was more beneficial, alongside a quality-of-life interaction p value of .09. What is the most accurate interpretation?
- Which statement most accurately summarizes the main finding about upper-limb function without extending it beyond the studied comparison?
- Which inference is not justified by this 21-child trial?
- A protocol delivered 2 hours per day, 5 days per week, for 10 weeks. What total dose does this represent, matching the trial’s stated dose?
- Which combination correctly matches group, mCIMT dose, and reported AHA change?
- A clinician wants to use the study to counsel a family about quality of life. Which wording is most evidence-calibrated?