Introduction to hematology
Pathology · Topic 13
Source: NMC CBME Curriculum 2024 · Volume I · Pathology · Topic 13 · combined PDF page 191
Practice questions
- In a digital hematology workflow, what is the most appropriate distinction between automated pre-classification and expert digital post-classification?
- A laboratory is considering digital morphology for routine leukocyte review. According to the review, which group is generally a less reliable target for current digital systems than common mature leukocytes?
- A digital system labels a rare cell as a blast, but the laboratory has not established the system's performance for blasts. What is the best next step?
- Which is an example of a broader application of digital morphology beyond automated cell pre-classification?
- Before implementing a digital morphology platform, which practice best addresses the review's stated requirements for clinical use?
- Which laboratory benefit is specifically associated with digital morphology in the review?
- A laboratory updates its digital morphology software. Which action is most consistent with the review's advice?
- Which statement best describes the relationship between digital morphology and other hematologic diagnostic data?
- A laboratory wants to use a digital morphology result in a clinical validation study. Which reporting feature is particularly important for interpreting its performance?
- In the reported acute dengue case, what prompted peripheral blood smear review?
- On which day after symptom onset did the reported dengue case show 25% activated lymphocytes and 5% suspected plasma cells on the peripheral smear?
- A patient with an appropriate acute dengue context has thrombocytopenia and suspected circulating plasma cells on smear. Which interpretation is best supported by the report?
- Which approximate time course for circulating plasmablasts or plasma cells is described in the dengue literature review?
- What is the appropriate interpretation of an increased very-high-fluorescence cell signal on a lymphocyte scattergram in suspected acute dengue?
- In the reported dengue case, how did the appearance of suspected circulating plasma cells relate temporally to the platelet count?
- Which limitation most directly prevents the reported dengue case from providing immunophenotypic confirmation of its suspected circulating plasma cells?
- A clinician sees transient circulating plasma cells and thrombocytopenia in a patient with suspected dengue. Which conclusion best respects the evidence described in the review?