Lymph node and spleen
Pathology · Topic 19
Source: NMC CBME Curriculum 2024 · Volume I · Pathology · Topic 19 · combined PDF page 192
Practice questions
- Which set lists the five categories retained by the WHO reporting system for lymph-node, spleen, and thymus cytopathology?
- A lymph-node FNAB specimen is too scant to support reliable cytomorphological classification. Which reporting category best fits this limitation?
- Which approach best reflects the recommended evaluation of lymphadenopathy when performing FNAB?
- Which imaging modality is specifically emphasized as important before and during lymph-node FNAB in the reviewed diagnostic approach?
- During an image-guided lymph-node FNAB, which role is attributed to rapid on-site evaluation (ROSE) in the reviewed framework?
- Which group of ancillary methods is identified as potentially complementing lymph-node cytomorphology in the WHO reporting framework?
- A report uses an atypical category. Which interpretation is most consistent with the five-category framework?
- What historical sequence is described for standardized lymph-node cytology reporting?
- A clinician asks for the numerical malignancy risk of a particular cytology category based only on the supplied review abstract. What is the most defensible response?
- Why can flow cytometry alone fail to answer a question about the regional arrangement of immune cells in a lymph node?
- A study aims to quantify the area of the follicular dendritic cell network within individual B-cell follicles. Which described analysis tool most directly addresses this aim?
- Which combination best describes the two Fiji (ImageJ)-based analysis approaches in the cited methods article?
- A researcher wants to adapt a lymph-node regional-architecture analysis to spleen tissue sections. What does the cited methods article indicate?
- Which statement best captures why tissue architecture matters in lymph nodes, according to the cited methods article?
- Which change is identified as capable of altering lymph-node architecture in the cited methods article?
- A laboratory has limited computational expertise and uses different antibody-staining panels. Which characterization of the described Fiji tools is supported by the methods article?
- Which interpretation of a shared 18F-FDG PET/CT pattern involving bone marrow, spleen, and lymph nodes is best supported by the FUO cohort study?
- In the reported FUO cohort, which groups were compared among patients exhibiting BSL-HMP?
- Which conclusion about the PET/CT-based high- and low-inflammatory-burden clusters is most appropriate?
- How many patients were included in the reported BSL-HMP cohort, and what were the group sizes?
- In the case report of MSMD with suspected evolving secondary HLH, which combination was described on cervical-node FNAC?
- In the MSMD case report, what was the appropriate significance assigned to hemophagocytosis observed on lymph-node FNAC?
- Which cells were specifically described as intact elements engulfed within macrophages in the lymph-node FNAC case?
- Which clinical context accompanied the lymph-node FNAC that raised concern for evolving HLH in the MSMD case?
- Which statement best describes the evidence level of the report linking MSMD, lymph-node hemophagocytosis, and possible evolving HLH?
- In the BSL-HMP cohort, what happened during follow-up to the 55 patients initially classified in the FUO group?
- In the exploratory clustering analysis, which treatment-related association was reported for the higher-inflammatory-burden cluster?
- Which conclusion about BSL-HMP and AOSD is justified by the cohort report?