Integrated Physiology
Physiology · Topic 12
Source: NMC CBME Curriculum 2024 · Volume I · Physiology · Topic 12 · combined PDF page 159
Practice questions
- In a review of people with type 2 diabetes without overt cardiovascular or pulmonary disease, which CPET finding was among those reported as reduced compared with non-diabetic subjects?
- A clinician wants a non-invasive provocative test that can provide multiparametric information about pulmonary, cardiovascular, muscular, and cellular oxidative systems during exercise. Which test best fits this description?
- Which pairing correctly matches a CPET measure with a finding reported in type 2 diabetes without overt cardiovascular or pulmonary disease?
- A study finds reduced peak workload and peak oxygen uptake in a person with type 2 diabetes. Which interpretation best reflects the review's conclusion about the underlying physiology?
- Which set contains only exercise-response measures reported as reduced in the reviewed type 2 diabetes population?
- A research team is organizing candidate mechanisms for reduced exercise tolerance in type 2 diabetes using the framework proposed in a review. Which list matches that framework?
- Two people with type 2 diabetes have similar reductions in peak oxygen uptake, but their other CPET findings differ. Which conclusion is most consistent with the reviewed integrated-physiology framework?
- Which description best captures the role of PPARα in intermediary metabolism according to the review?
- Which pathway is included among those regulated by PPARα in the review?
- A question asks which process is included in the review's map of PPARα-regulated metabolism, in addition to fatty-acid oxidation. Which is the best answer?
- When considering PPARα's metabolic effects, which distinction does the review explicitly make?
- Which two adipocyte lipases are identified as important for controlling lipolysis in the review?
- A researcher proposes that a lipid-droplet surface protein can regulate lipolysis by limiting or permitting lipase access to stored triglyceride. Which protein best fits the review's description?
- Which signaling description best matches the prototype hormonal control of adipocyte lipolysis in the review?
- Which statement about lipolysis in obesity is consistent with the review?
- In intestinal L cells, which proglucagon-processing enzyme and peptide set are paired correctly in the reviewed account?
- In pancreatic alpha cells, which enzyme is associated with production of glucagon from proglucagon in the reviewed account?
- How can one prohormone give rise to different sets of biologically active peptides in different tissues, according to the review?
- What broad physiological functions of renal organic-anion transport proteins are emphasized in the review?
- A study of proximal tubular organic-anion handling focuses on proteins that help form a functional multimolecular complex, particularly at the apical membrane. Which proteins are highlighted in the review?
- What possible additional role for dicarboxylate anions is raised by the proximal tubular transport review?
- A review of sheep fetal physiology considers what determines fetal water volume. Which conclusion best reflects its integrated account?
- According to the sheep fetal-volume review, which statement about placental water entry is correct?
- A pancreatic disease research group is planning work on normal physiology and disease mechanisms. Which approach best reflects the workshop's stated conclusion?