Schizophrenia and other Psychotic disorders
Psychiatry · Topic 4
Source: NMC CBME Curriculum 2024 · Volume II · Psychiatry · Topic 4 · combined PDF page 352
Practice questions
- In the 2024 meta-analysis of olfactory function in schizophrenia-spectrum disorders, which pattern was reported relative to healthy controls?
- A clinician is interpreting odor-identification results from a patient with a schizophrenia-spectrum disorder. Which set of variables was reported to moderate odor-identification performance in the meta-analysis?
- Which statement best characterizes the evidence base of the updated meta-analysis of olfactory function in schizophrenia-spectrum disorders?
- Which group of epigenetic mechanisms was considered in human case-control studies in the systematic review of schizophrenia and other psychotic disorders?
- Which conclusion is most appropriately supported by the systematic review of human epigenetic findings in schizophrenia and other psychotic disorders?
- Which model of gene-environment interplay is consistent with the epigenetics review's account of schizophrenia and other psychotic disorders?
- In a meta-analysis of 31 studies involving homeless people, what was the pooled prevalence estimate for schizophrenia?
- The pooled prevalence estimate for psychosis among homeless people had an I² of 99.43%. What is the most appropriate interpretation?
- Which geographic pattern did the homelessness meta-analysis report for pooled prevalence estimates?
- In comparative real-world data summarized by a systematic review, how did once-monthly paliperidone palmitate (PP1M) compare with oral antipsychotics on relapse-related events?
- In a randomized, double-blind comparison summarized in the PP1M systematic review, which finding was reported for PP1M versus haloperidol decanoate?
- Which prolactin-related finding did the systematic review report when comparing PP1M with haloperidol decanoate?
- Compared with PP1M, what movement-related pattern did the review report for patients receiving haloperidol decanoate?
- Which statement best reflects the review's findings on healthcare costs and study completion with PP1M?
- What was the overall conclusion of the systematic review of group cognitive-behavioral treatment for schizophrenia and other psychotic disorders?
- Which set of outcomes was within the reported benefits of group CBT plus standard treatment in the systematic review?
- A trainee claims that the group-CBT review proves that every group CBT program produces the same benefit in every patient with psychosis. Which appraisal is best?
- What pooled incidence rate ratio for schizophrenia did the England meta-analysis report for Black Caribbean groups relative to the baseline population?
- Which interpretation best fits the systematic review of psychosis incidence in Black Caribbean groups in England from 1950 to 2013?
- The review reported a weak association between more urban settings and smaller schizophrenia incidence rate ratios, with an odds ratio of 0.98 and p = 0.06. Which interpretation is most appropriate?
- What pooled prevalence of antipsychotic polypharmacy did the 2026 MENAT/EMRO meta-analysis report?
- Across nine studies in the MENAT/EMRO review, what proportion of patients was reported to be receiving clozapine?
- The MENAT/EMRO meta-analysis reported an I² of 98.4% for antipsychotic polypharmacy prevalence. What does this most strongly indicate?
- Which structures receive major cholinergic projections from the basal forebrain cholinergic nuclei, according to the review?
- Which cognitive functions are particularly relevant to the basal forebrain cholinergic projections discussed in the psychosis review?
- Which statement best reflects the review's account of cholinergic alterations in schizophrenia and other psychotic disorders?