Stress related disorders
Psychiatry · Topic 8
Source: NMC CBME Curriculum 2024 · Volume II · Psychiatry · Topic 8 · combined PDF page 353
Practice questions
- In a meta-analysis of fear conditioning in anxiety- and stress-related disorders, which pattern was reported during fear acquisition?
- During extinction and extinction recall, which finding best reflects the meta-analysis of fear conditioning?
- Which statement about CS+/CS− differentiation is supported by the fear-learning meta-analysis?
- A clinician is discussing the fear-learning meta-analysis with a patient and wants to avoid overstating the results. Which conclusion is best supported?
- The fear-learning meta-analysis included which approximate total sample?
- In adults with major depressive disorder, what association with childhood maltreatment was supported by the meta-analysis?
- For depression symptom severity in adults with major depressive disorder, which pooled estimate was reported for childhood maltreatment?
- The meta-analysis also reported an association between childhood maltreatment and anxiety symptoms in adults with major depressive disorder. Which interpretation is most accurate?
- A question asks whether childhood maltreatment reliably predicts recurrence or suicidality in stress-related disorders. What conclusion is best supported by the supplied systematic review?
- Which limitation most constrains conclusions about childhood maltreatment and clinical features in anxiety and stress-related disorders in the reviewed evidence?
- A developmental-age review discusses genetic findings after early trauma. Which interpretation is most consistent with that review?
- Which group of genes was among those discussed in the developmental-age review as associated with stress-related vulnerability or resilience?
- A family asks whether genetic research can currently provide precise individualized predictions of stress-related disorders in children. Which response best reflects the developmental-age review?
- A qualitative meta-synthesis asked people with stress-related disorders what they experienced as supportive for recovery. Which set of themes was identified?
- Which statement best captures the role of patient preference in the recovery-support synthesis?
- A patient asks whether a supportive atmosphere alone has been proven by this qualitative synthesis to cure a stress-related disorder. Which reply is most accurate?
- A systematic review of intranasal oxytocin trials in PTSD used fMRI. Which neural finding was reported for PTSD participants?
- In the oxytocin fMRI review, what was reported in studies of social anxiety disorder?
- A clinician interprets the oxytocin review as evidence that intranasal oxytocin is established standard treatment for every patient with PTSD or social anxiety disorder. Which appraisal is most appropriate?
- Which factors were reported to influence oxytocin-related effects in the PTSD studies reviewed?
- A systematic review of metabolomics in MDD, bipolar disorder, and PTSD identified four metabolites consistently altered across disorders. Which set was reported?
- The metabolomics review found candidate shared metabolic changes across MDD, bipolar disorder, and PTSD. What is the most appropriate present-day interpretation of those findings?
- Which broad metabolic areas were highlighted by pathway enrichment in the metabolomics review?
- A review of intimate partner violence and stress-related disorders discusses several proposed biological pathways. Which combination is consistent with the review?
- A research team cites the IPV review to claim that epigenetic changes provide a definitive diagnostic test for stress-related disorders in survivors. Which response is best supported?
- A clinician wants to counsel a survivor of intimate partner violence using the IPV review. Which statement is most defensible?
- A clinician is asked whether a metabolite panel, an oxytocin fMRI response, or a fear-conditioning result can replace diagnostic assessment for acute stress disorder or adjustment disorder. What is the best answer based on the supplied literature?